Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465572 | 1.00 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29494130 | 1.00 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5354758 | 1.00 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28374465 | 0.98 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL818887 | 0.97 | GRIN2D (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL3824137 | 0.97 | GRIN2D (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29695697 | 0.94 | GRIN2D (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15840501 | 0.93 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4425088 | 0.93 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4425093 | 0.93 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024354-B | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117024354-A | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-117024354-B | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117049999-A | Preparation method of Nemactetvir intermediate | 重庆博腾制药科技股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-117024354-A | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2023151188-A1 | GREEN SYNTHESIS METHOD OF ANTIVIRAL DRUG INTERMEDIATE | 上海皓元医药股份有限公司 | 2023-08-17 | — | — | WO | disclosed |
| CN-115385984-A | Peptide-like derivative, preparation method and application | 北京科翔中升医药科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-114671798-B | Green synthesis method of antiviral drug intermediate | 上海皓元医药股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-114671798-A | Green synthesis method of antiviral drug intermediate | 上海皓元医药股份有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-114057627-B | Preparation method of hepatitis C and neocorolla drug intermediate and salt thereof | 南京桦冠生物技术有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114057627-A | Preparation method of hepatitis C and neocorolla drug intermediate and salt thereof | 南京桦冠生物技术有限公司 | 2022-02-18 | — | — | CN | disclosed |
| WO-2005103095-A1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
| US-20050059786-A1 | Process for the co-oligomerisation of ethylene and alpha olefins | DE BOER ERIC JOHANNES MARIA (NL) | 2005-03-17 | — | — | US | disclosed |
| US-20040087434-A1 | Chromium catalysts active in olefin polymerization | REPSOL QUIMICA, S.A. (ES) | 2004-05-06 | — | — | US | disclosed |
| EP-1325924-A1 | Chromium catalysts active in olefin polymerisation | REPSOL QUIMICA S.A. (ES) | 2003-07-09 | — | — | EP | disclosed |
| EP-1325925-A1 | Chromium catalysts active in olefin polymerization | REPSOL QUIMICA S.A. (ES) | 2003-07-09 | — | — | EP | disclosed |
| EP-1322576-A2 | PROCESS FOR THE CO-OLIGOMERISATION OF ETHYLENE AND ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2003-07-02 | — | — | EP | disclosed |
| US-20020128409-A1 | Process for the co-oligomerisation of ethylene and alpha olefins | SHELL OIL COMPANY | 2002-09-12 | — | — | US | disclosed |
| WO-2002028805-A2 | PROCESS FOR THE CO-OLIGOMERISATION OF ETHYLENE AND ALPHA OLEFINS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2002-04-11 | — | — | WO | disclosed |
| EP-1059313-A1 | Transition metal catalyst component for polymerization, aromatic vinyl compound-olefin copolymer and process for its production by means of the catalyst component | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087434-A1 | Chromium catalysts active in olefin polymerization | CBR1, SCO2, CBR3 | GRIN2D 3369/4885GRIN3B 2635/4885GRIN1 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.