Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3824137 | 1.00 | GRIN2D (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5354758 | 0.97 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL819043 | 0.97 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31465572 | 0.97 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29494130 | 0.97 | GRIN2D (0.45) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28374465 | 0.95 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29695697 | 0.91 | GRIN2D (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15840501 | 0.90 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4425088 | 0.90 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15906747 | 0.90 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617311-A1 | POLYMER BLEND FOR THE PRODUCTION OF A MONO-AXIALLY ORIENTED FILM | Basell Polyolefine GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| US-12415911-B2 | Polyethylene composition for filaments or fibers | BASELL POLYOLEFINE GMBH (DE) | 2025-09-16 | — | — | US | disclosed |
| EP-4567066-A1 | POLYETHYLENE COMPOSITION FOR STRAPS | Basell Polyolefine GmbH (DE) | 2025-06-11 | — | — | EP | disclosed |
| EP-4567064-A1 | POLYETHYLENE COMPOSITION FOR STRAPS, COMPRISING RECYCLATE POLYETHYLENE | Basell Polyolefine GmbH (DE) | 2025-06-11 | — | — | EP | disclosed |
| EP-4516840-A1 | POLYMER BLEND FOR THE PRODUCTION OF A MONO-AXIALLY ORIENTED FILM | Basell Polyolefine GmbH (DE) | 2025-03-05 | — | — | EP | disclosed |
| EP-4516839-A1 | MONO-AXIALLY ORIENTED POLYETHYLENE FILM | Basell Polyolefine GmbH (DE) | 2025-03-05 | — | — | EP | disclosed |
| EP-4516841-A1 | POLYMER BLEND FOR THE PRODUCTION OF A BIORIENTED POLYMER FILM | Basell Polyolefine GmbH (DE) | 2025-03-05 | — | — | EP | disclosed |
| US-11999839-B2 | Polyethylene composition for filaments or fibers | BASELL POLYOLEFINE GMBH (DE) | 2024-06-04 | — | — | US | disclosed |
| EP-4069774-B1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-20230075830-A1 | POLYETHYLENE COMPOSITION FOR FILAMENTS OR FIBERS | BASELL POLYOLEFINE GMBH (DE) | 2023-03-09 | — | — | US | disclosed |
| US-20110212283-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110212315-A1 | Impact Resistant LLDPE Composition and Films Made Thereof | BASELL POLYOLEFINE GMBH (DE) | 2011-09-01 | — | — | US | disclosed |
| US-8008403-B2 | Polyethylene and catalyst composition for its preparation | BASELL POLYOLEFINE GMBH (DE) | 2011-08-30 | — | — | US | disclosed |
| EP-2322565-A2 | Catalyst composition for the preparation of polyethylene | Basell Polyolefine GmbH (DE) | 2011-05-18 | — | — | EP | disclosed |
| US-20110045295-A1 | ADHESIVE POLYMER COMPOSITION | BASELL POLYOLEFINE GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2236577-A2 | Polyethylene composition | Basell Polyolefine GmbH (DE) | 2010-10-06 | — | — | EP | disclosed |
| EP-1113025-B1 | Catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL CO (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20080286509-A1 | Polyethylene and Catalyst Composition for Its Preparation | BASELL POLYOLEFINE GMBH (DE) | 2008-11-20 | — | — | US | disclosed |
| US-7202316-B2 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-10 | — | — | US | disclosed |
| US-20050192178-A1 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-01 | — | — | US | disclosed |