Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenylpropanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.83 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpropanol SCHEMBL27734478 | 0.93 | LMNA (0.86) | LMNABCAT2KDM4EL3MBTL1NPC1 | |
| Phenylpropanol SCHEMBL27691663 | 0.91 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL698860 | 0.91 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL539164 | 0.91 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL27878996 | 0.91 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL56673 | 0.91 | LMNA (1.00) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL8934222 | 0.89 | LMNA (0.79) | LMNABCAT2KDM4EL3MBTL1NPC1 | |
| Phenylpropanol SCHEMBL19667852 | 0.89 | LMNA (0.95) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL11694956 | 0.89 | LMNA (0.95) | LMNAKDM4EL3MBTL1AOC3RIPK1 | |
| Phenylpropanol SCHEMBL9994261 | 0.89 | LMNA (0.95) | LMNAKDM4EL3MBTL1AOC3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116672761-A | Capillary gas chromatography chiral separation column based on chiral metal organic macrocyclic material | 云南师范大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-109418922-A | A kind of Rosemary health-protection soy sauce and preparation method thereof | 青岛生鲜馆电子商务有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-108743169-A | A kind of macro Chinese traditional medicine molecule osmotic absorption therapeutic bed for treating lumbar vertebra disease | 卫景龙 | 2018-11-06 | — | — | CN | disclosed |
| CN-108578488-A | A kind of Lear dormancy piece and preparation method thereof | 广西玉兰制药有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108403891-A | Chinese medicine composition for treating abdominal post-operation Early selection sticks and its production method | 南充市中心医院 | 2018-08-17 | — | — | CN | disclosed |
| CN-104911074-B | A kind of new temperature compensation Lycium chinense wine | 宁夏好劲来生物科技有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-107074801-A | Aryl and arylalkyl substituted pyrazolyl and pyrimidinyl tricyclenones as antioxidant inflammatory modulators | 里亚塔医药公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-106631809-A | Green synthesis method for preparing nitroalkane by oxidizing oxime | 南京工业大学 | 2017-05-10 | — | — | CN | disclosed |
| CN-105463604-A | Preparation method of regenerated cellulose fiber containing cinnamon oil microcapsule | JIANGSU GOLDSUN TEXTILE TECH CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105456403-A | Preparation method of liermian capsule | CHENGDU JIUZHITANG JINDING PHARMACEUTICAL CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-1674862-A | Perfume composition | KAO CORP (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1582766-A | Health care chickens and their cooking method | LIU WENYU (CN) | 2005-02-23 | — | — | CN | disclosed |
| CN-1539470-A | External Chinese patent medicines for curing periarthritis humeroscapularis and myotenositis | 徐小杰 | 2004-10-27 | — | — | CN | disclosed |
| EP-0801642-B1 | NOVEL SULFAMATE COMPOUND CONTAINING N-SUBSTITUTED CARBAMOYL GROUP AND METHOD FOR PREPARING THE SAME | YUKONG LTD (KR) | 2000-12-20 | — | — | EP | disclosed |
| CN-1055848-C | Traditional Chinese set prescription for curing gastrointestinal tract disease and gynopathy | TRADITIONAL CHINESE MEDICAL HO (CN) | 2000-08-30 | — | — | CN | disclosed |
| CN-1209323-A | Chinese medicinal composition for treating uremia, renal failure and nephrotic syndrome | GE ZHENHUA (CN) | 1999-03-03 | — | — | CN | disclosed |
| CN-1174709-A | Traditional Chinese set prescription for curing gastrointestinal tract disease and gynopathy | TRADITIONAL CHINESE MEDICIAL H (CN) | 1998-03-04 | — | — | CN | disclosed |
| EP-0801642-A1 | NOVEL SULFAMATE COMPOUND CONTAINING N-SUBSTITUTED CARBAMOYL GROUP AND METHOD FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1997-10-22 | — | — | EP | disclosed |
| WO-1997016418-A1 | NOVEL SULFAMATE COMPOUND CONTAINING N-SUBSTITUTED CARBAMOYL GROUP AND METHOD FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1997-05-09 | — | — | WO | disclosed |
| CN-1123139-A | \"Tonglian\"-natural health-care bath lotion capable of permeating skin and preparation thereof | ZHAO XINSHENG (CN) | 1996-05-29 | — | — | CN | disclosed |