Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190988 | 0.89 | PPIA (0.42) | MRGPRX4PPIAPTPN1PTGER1CYP2C9 | |
| SCHEMBL6205852 | 0.85 | CYP2C9 (0.46) | PTGER1CYP2C9BRD4 | |
| SCHEMBL8126711 | 0.81 | CYP19A1 (0.44) | MRGPRX4PPIAPTPN1PTGER1CYP2C9 | |
| SCHEMBL31088233 | 0.78 | CYP2C9 (0.43) | MRGPRX4PTGER1CYP2C9BRD4 | |
| SCHEMBL8197532 | 0.78 | MRGPRX4 (0.38) | MRGPRX4PPIAPTGER1CYP19A1MAOB | |
| SCHEMBL15014407 | 0.78 | CYP2C9 (0.48) | MRGPRX4PTGER1CYP2C9CYP19A1BRD4 | |
| SCHEMBL5357518 | 0.77 | CYP2C9 (0.45) | MRGPRX4PPIAPTGER1CYP2C9CYP19A1 | |
| SCHEMBL29424444 | 0.77 | CYP2C9 (0.45) | MRGPRX4PPIAPTGER1CYP2C9CYP19A1 | |
| SCHEMBL8180809 | 0.76 | MRGPRX4 (0.36) | MRGPRX4PPIAPTGER1CYP19A1MAOB | |
| SCHEMBL22304234 | 0.76 | CYP2C9 (0.44) | MRGPRX4PTGER1CYP2C9CYP19A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060608-A | ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-05-09 | — | — | US | disclosed |