Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197532 | 0.92 | MRGPRX4 (0.38) | MRGPRX4CYP19A1CYP11B1CYP11B2ABCB1 | |
| SCHEMBL8321897 | 0.86 | MTNR1A (0.40) | CACNA1B | |
| SCHEMBL8132245 | 0.82 | MRGPRX4 (0.36) | MRGPRX4CYP19A1CYP11B1CYP11B2ABCB1 | |
| SCHEMBL8191113 | 0.81 | PTGER1 (0.33) | MRGPRX4CYP19A1CYP11B1CYP11B2ABCB1 | |
| SCHEMBL8317086 | 0.78 | HDAC8 (0.40) | — | |
| SCHEMBL8190897 | 0.76 | MRGPRX4 (0.40) | MRGPRX4CYP19A1PTGER1PPIAMAOB | |
| SCHEMBL14502597 | 0.74 | GLRA1 (0.35) | MRGPRX4CYP19A1PTGER1MAOB | |
| SCHEMBL8131442 | 0.74 | MRGPRX4 (0.39) | MRGPRX4CACNA1B | |
| SCHEMBL7953762 | 0.73 | L3MBTL1 (0.38) | MRGPRX4PTGER1 | |
| SCHEMBL8127756 | 0.73 | MRGPRX4 (0.40) | MRGPRX4CYP19A1CYP11B1CYP11B2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060608-A | ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-05-09 | — | — | US | disclosed |