SCHEMBL819137

SCHEMBL819137

Cc1ccccc1C(=O)C(C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.47
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
MYC P01106 1/20 0.43
MAPK13 O15264 1/20 0.43
MAPK12 P53778 1/20 0.43
MAPK11 Q15759 1/20 0.43
MAPK14 Q16539 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 2/20 0.42
ITGB1 P05556 1/20 0.41
ITGA5 P08648 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13871510 0.85 KMT2A (0.46) HPGDERCC5FEN1ALDH1A1KMT2A
SCHEMBL29588714 0.85 KMT2A (0.46) HPGDERCC5FEN1ALDH1A1KMT2A
SCHEMBL8391903 0.82 HPGD (0.44) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL585832 0.81 HPGD (0.47) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL8114356 0.81 ERCC5 (0.43) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL11718733 0.81 HPGD (0.44) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL13212819 0.79 SLC6A2 (0.40) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL18073993 0.79 KMT2A (0.47) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL14297428 0.79 HPGD (0.46) HPGDERCC5FEN1SLC6A2SLC6A4
SCHEMBL1685076 0.79 HPGD (0.46) HPGDERCC5FEN1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368127-B Compounds and their use as EP4 receptor antagonists 武田药品工业株式会社 2020-12-11 CN disclosed
US-9580571-B2 Aromatic acylation with cyclic anhydride for plasticizer production EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-02-28 US disclosed
US-9512296-B2 Aromatic acylation with cyclic anhydride for plasticizer production EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-12-06 US disclosed
US-20140100383-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-04-10 US disclosed
US-20140100384-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2014-04-10 US disclosed
US-8604114-B2 Aromatic acylation with cyclic anhydride for plasticizer production EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-12-10 US disclosed
US-20110160371-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION EXXONMOBILE RESEARCH AND ENGINEERING COMPANY (US) 2011-06-30 US disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-6126855-A Reaction products of lyotropic liquid crystal salt complexes ELLIOTT STANLEY B (US) 2000-10-03 US disclosed
US-5833877-A DIAGMAGNETIC COMPLEX; SUPERCONDUCTORS ELLIOTT STANLEY B (US) 1998-11-10 US disclosed
WO-1998001511-A1 REACTION PROCUCTS OF LYOTROPIC LIQUID CRYSTAL SALT COMPLEXES ELLIOTT STANLEY B (US) 1998-01-15 WO disclosed
US-5595683-A COMPLEX OF METAL SALT OF BENZOYLPROPIONIC ACID, LATTICE MODIFIER, CYCLIZATION, HUMIDITY SENSORS ELLIOTT STANLEY B (US) 1997-01-21 US disclosed
US-5573999-A FUNGICIDES AND INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-12 US disclosed
US-5443753-A Reaction products of lyotropic liquid crystal salt complexes ELLIOTT STANLEY B (US) 1995-08-22 US disclosed
US-5354499-A Reaction products of lyotropic liquid crystal salt complexes ELLIOTT STANLEY B (US) 1994-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160371-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION ACAD11, ACOT7, ACOX3 HPGD 523/4885ERCC5 4369/4885FEN1 3926/4885
US-20140100383-A1 AROMATIC ACYLATION WITH CYCLIC ANHYDRIDE FOR PLASTICIZER PRODUCTION ACAD11, ACOT7, ACOX3 HPGD 523/4885ERCC5 4369/4885FEN1 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.