SCHEMBL819155

SCHEMBL819155

O=S(=O)(O)CCc1ccncc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
NPC1 O15118 1/20 0.53
ALDH1A1 P00352 3/20 0.47
LOXL2 Q9Y4K0 2/20 0.46
RAB9A P51151 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
HRH1 P35367 2/20 0.41
MEN1 O00255 2/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9343856 0.98 KMT2A (0.51) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL9479042 0.98 KMT2A (0.51) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL17508105 0.98 KMT2A (0.51) KMT2ANPC1ALDH1A1LOXL2RAB9A
Formamide SCHEMBL11293812 0.92 NPC1 (0.47) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL14720079 0.91 KMT2A (0.50) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL10917591 0.88 NPC1 (0.50) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL29074464 0.80 LMNA (0.50) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL14194326 0.78 KMT2A (0.53) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL4250874 0.78 RECQL (0.59) KMT2ANPC1ALDH1A1LOXL2RAB9A
SCHEMBL1272598 0.78 KMT2A (0.58) KMT2ANPC1ALDH1A1LOXL2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009655-A1 METHOD FOR PRODUCING A CATALYST COMPRISING AT LEAST ONE GROUP VIB METAL, AT LEAST ONE GROUP VIIIB METAL AND A CARRIER BASED ON OXIDE(S) IFP Energies Nouvelles (FR) 2024-01-11 US claimed
US-11827995-B2 In-situ method for synthesizing Ni—w—Wc composite coating SOOCHOW UNIVERSITY (CN) 2023-11-28 US claimed
EP-4263055-A1 METHOD FOR PRODUCING A CATALYST COMPRISING AT LEAST ONE GROUP VIB METAL, AT LEAST ONE GROUP VIIIB METAL AND A CARRIER BASED ON OXIDE(S) IFP Energies nouvelles (FR) 2023-10-25 EP claimed
US-20230279573-A1 AN IN-SITU METHOD FOR SYNTHESIZING NI-W-WC COMPOSITE COATING SOOCHOW UNIVERSITY (CN) 2023-09-07 US claimed
CN-115787012-A Preparation method of low-stress self-lubricating high-tungsten Ni-W alloy coating 苏州大学 2023-03-14 CN claimed
WO-2023015602-A1 IN-SITU SYNTHESIS METHOD FOR NI-W-WC COMPOSITE PLATING 苏州大学 2023-02-16 WO claimed
CN-113390865-B Acid-base indicating test paper and preparation method and application thereof 浙江工业大学 2022-11-18 CN claimed
CN-113755916-B In-situ synthesis method of Ni-W-WC composite coating 苏州大学 2022-07-12 CN claimed
WO-2022128491-A1 METHOD FOR PRODUCING A CATALYST COMPRISING AT LEAST ONE GROUP VIB METAL, AT LEAST ONE GROUP VIIIB METAL AND A CARRIER BASED ON OXIDE(S) IFP Energies Nouvelles (FR) 2022-06-23 WO claimed
CN-113755916-A In-situ synthesis method of Ni-W-WC composite coating 苏州大学 2021-12-07 CN claimed
EP-0060028-B1 CEPHALOSPORIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION AJINOMOTO CO., INC. (JP) 1985-12-04 EP claimed
US-4546176-A 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same EISAI CO., LTD. (JP) 1985-10-08 US claimed
US-4423215-A REACTING ESTER, SODIUM IODIDE, 4-PYRIDINEETHANESULFONIC ACID AJINOMOTO COMPANY, INC. (JP) 1983-12-27 US claimed
EP-0026542-B1 PREPARATION OF ESTERS CONTAINING AN ALPHA CYANO GROUP IN THE ALCOHOL PORTION OF THE ESTER FMC Corporation (US) 1982-12-15 EP claimed
EP-0060028-A1 Cephalosporin derivatives and process for their preparation AJINOMOTO CO., INC. (JP) 1982-09-15 EP claimed
EP-0058505-A1 Preparation of esters containing an alpha-cyano group in the alcohol portion of the esters FMC Corporation (US) 1982-08-25 EP claimed
US-4322535-A REACTION OF AN ACYL HALIDE, ALDEHYDE, AND CYANIDE SALT USING A CATALYTIC AMPHOTERIC SURFACTANT OF AN AMINO ALKYLSULFONATE FMC CORPORATION (US) 1982-03-30 US claimed
US-4254051-A ALPHA-CYANO ESTERS BY REACTING AN ACYL HALIDE WITH 3-PHENOXYBENZALDEHYDE AND A CYANIDE SALT FMC CORPORATION (US) 1981-03-03 US claimed
US-4217450-A ANTIBIOTICS, BACTERICIDES AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-12 US claimed
US-4009087-A N-HETERO AROMATIC, AND SULFOALKYL OR SULFOARYL SULFIDE M&T CHEMICALS INC. (US) 1977-02-22 US claimed