Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784672 | 0.83 | TDP1 (0.46) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16856847 | 0.79 | TDP1 (0.39) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31481283 | 0.77 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2773204 | 0.76 | TDP1 (0.54) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12898049 | 0.75 | TDP1 (0.39) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5055510 | 0.75 | TDP1 (0.39) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3769047 | 0.75 | PDE10A (0.51) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL27643164 | 0.74 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29401720 | 0.74 | TDP1 (0.52) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28042070 | 0.73 | SMN1; SMN2 (0.45) | TDP1TSHRSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103613581-A | Preparation method for Dexiansoprazole | SHANDONG INST PHARMACEUTICAL INDUSTRY | 2014-03-05 | — | — | CN | disclosed |
| US-20110028518-A1 | DEXLANSOPRAZOLE PROCESS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-02-03 | — | — | US | disclosed |
| US-20110028518-A1 | DEXLANSOPRAZOLE PROCESS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-02-03 | — | — | US | disclosed |
| WO-2009117489-A1 | DEXLANSOPRAZOLE PROCESS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |
| WO-2000000474-A1 | PYRIDINE BUILDING BLOCKS AS INTERMEDIATES IN THE SYNTHESIS OF PHARMACEUTICALLY ACTIVE COMPOUNDS | RUSSINSKY LIMITED (IE) | 2000-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028518-A1 | DEXLANSOPRAZOLE PROCESS AND POLYMORPHS | CYP2C19, CYP3A4, CYP2D6 | TDP1 1998/4885TSHR 2051/4885SMN1; SMN2 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.