Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | GHSR | Q92847 | 4/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199282 | 1.00 | ACACB (0.48) | ACACBMAOAMAOBITGB3ITGA2B | |
| SCHEMBL8192077 | 1.00 | ACACB (0.48) | ACACBMAOAMAOBITGB3ITGA2B | |
| SCHEMBL8192688 | 0.88 | CYP26A1 (0.45) | — | |
| SCHEMBL8200806 | 0.88 | CYP26A1 (0.45) | — | |
| SCHEMBL8192685 | 0.88 | CYP26A1 (0.45) | — | |
| SCHEMBL8198784 | 0.85 | ITGB3 (0.55) | ACACBMAOAMAOBITGB3ITGA2B | |
| SCHEMBL8200699 | 0.85 | ITGB3 (0.55) | ACACBMAOAMAOBITGB3ITGA2B | |
| SCHEMBL8198782 | 0.85 | ITGB3 (0.55) | ACACBMAOAMAOBITGB3ITGA2B | |
| SCHEMBL7911568 | 0.81 | MAOB (0.52) | MAOAMAOBITGB3ITGA2BHRH3 | |
| SCHEMBL5665208 | 0.79 | MAOB (0.52) | MAOAMAOBITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048877-A | Tetralone derivatives as antiarrhythmic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-04-11 | — | — | US | disclosed |