Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 3/20 | 0.43 |
| ▸ | POR | P16435 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337802 | 0.90 | NQO1 (0.48) | NQO1PORELANENPC1ALDH1A1 | |
| SCHEMBL8029684 | 0.78 | STAT3 (0.38) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL3331249 | 0.72 | NQO1 (0.50) | NQO1PORELANENPC1ALDH1A1 | |
| SCHEMBL8260282 | 0.69 | NQO1 (0.52) | NQO1PORELANEALDH1A1NFKB1 | |
| SCHEMBL3333295 | 0.69 | STAT3 (0.42) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6052838 | 0.64 | NQO1 (0.57) | NQO1PORELANEALDH1A1 | |
| Alpha-Dunnione SCHEMBL940069 | 0.63 | NQO1 (0.56) | NQO1PORELANENPC1ALDH1A1 | |
| SCHEMBL6052899 | 0.62 | NQO1 (0.67) | NQO1PORELANEALDH1A1 | |
| (3R)-Dunnione SCHEMBL103115 | 0.62 | NQO1 (0.63) | NQO1PORELANENPC1ALDH1A1 | |
| SCHEMBL5940500 | 0.61 | NQO1 (0.48) | NQO1PORALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008066299-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND PREVENTION OF DISEASES INVOLVING IMPOTENCE | MAZENCE INC. (KR) | 2008-06-05 | — | — | WO | disclosed |