Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | MPC2 | O95563 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247602 | 0.86 | PPARG (0.66) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL8173333 | 0.86 | CA2 (0.66) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL13846962 | 0.83 | CA2 (0.58) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL3073739 | 0.78 | CA2 (1.00) | CA2PPARGFFAR1MAOBMEN1 | |
| SCHEMBL8173780 | 0.78 | CA2 (0.59) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL8179494 | 0.78 | CA2 (0.81) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL8187284 | 0.77 | CA2 (0.72) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL8172766 | 0.77 | SIRT2 (0.68) | CA2FFAR1PTPN1MEN1KMT2A | |
| SCHEMBL8179749 | 0.76 | CA2 (0.68) | CA2PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL8198423 | 0.76 | CA2 (0.64) | CA2PTPN1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |