Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183622 | 0.93 | ACACB (0.37) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8184881 | 0.91 | ACACB (0.35) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8175218 | 0.91 | ACACB (0.36) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8189038 | 0.91 | PGK1 (0.38) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8179729 | 0.90 | ACACB (0.35) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8184729 | 0.89 | CFTR (0.35) | ACACBCFTRFLT1KDRKDM4E | |
| SCHEMBL8180999 | 0.89 | SYK (0.39) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8179960 | 0.89 | TNF (0.37) | ACACBCFTRFLT1KDRSMN1; SMN2 | |
| SCHEMBL8184731 | 0.88 | ACACB (0.38) | ACACBCFTRFLT1KDRTP53 | |
| SCHEMBL8175450 | 0.88 | CFTR (0.35) | ACACBCFTRFLT1KDRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077557-A1 | 8-ETHINYLXANTHINE DERIVATIVES AS SELECTIVE A2A RECEPTOR ANTAGONISTS | SCHWARZ PHARMA AG (DE) | 2008-07-03 | — | — | WO | disclosed |