Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 12/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189656 | 0.85 | FAP (0.35) | FAPPREPPSMB5F2 | |
| SCHEMBL13336391 | 0.85 | FAP (0.35) | FAPPREPPSMB5F2 | |
| SCHEMBL13363192 | 0.85 | FAP (0.35) | FAPPREPPSMB5F2 | |
| SCHEMBL13573875 | 0.77 | PREP (0.34) | FAPPREPPSMB5F2 | |
| SCHEMBL8189130 | 0.77 | PREP (0.34) | FAPPREPPSMB5F2 | |
| SCHEMBL13336393 | 0.77 | FAP (0.36) | FAPPREPPSMB5F2 | |
| SCHEMBL13363332 | 0.77 | FAP (0.36) | FAPPREPPSMB5F2 | |
| SCHEMBL8201674 | 0.77 | FAP (0.36) | FAPPREPPSMB5F2 | |
| SCHEMBL13573876 | 0.74 | PREP (0.36) | FAPPREPPSMB5F2 | |
| SCHEMBL8191736 | 0.74 | PREP (0.36) | FAPPREPPSMB5F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070733-A2 | MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PHENOMIX CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |