Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203991 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL8200993 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL27723934 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL5572207 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL14214178 | 0.79 | MEN1 (0.59) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL4443244 | 0.79 | BRD4 (0.68) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL15348811 | 0.76 | GAA (0.64) | SMN1; SMN2CYP1A2CYP2C19GAAL3MBTL1 | |
| SCHEMBL21059156 | 0.75 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP1A2CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL3386794 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL7790395 | 0.75 | SMN1; SMN2 (0.65) | SMN1; SMN2CYP1A2CYP2C19L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000169449-A | NEW PRODUCTION INTERMEDIATE FOR FLUORINE-CONTAINING 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVE | BANYU PHARMACEUT CO LTD | 2000-06-20 | — | — | JP | disclosed |