Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240404 | 1.00 | SLC2A1 (0.47) | SLC2A1ADRB3ADRB1KDM1AALOX15 | |
| SCHEMBL9118203 | 0.83 | LDHA (0.51) | ADRB3ADRB1LDHAADRB2GLA | |
| SCHEMBL9118197 | 0.83 | LDHA (0.51) | ADRB3ADRB1LDHAADRB2GLA | |
| SCHEMBL9118214 | 0.83 | LDHA (0.51) | ADRB3ADRB1LDHAADRB2GLA | |
| SCHEMBL7618748 | 0.82 | POLB (0.48) | ADRB3ADRB1KDM1AALOX15ALOX12 | |
| SCHEMBL7148487 | 0.81 | SLC2A1 (0.69) | SLC2A1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL8301319 | 0.81 | SLC2A1 (0.69) | SLC2A1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL7148491 | 0.81 | SLC2A1 (0.69) | SLC2A1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL7211873 | 0.81 | SLC2A1 (0.69) | SLC2A1ADRB3ADRB1ADRB2GLA | |
| SCHEMBL7207159 | 0.80 | ADRB3 (0.55) | SLC2A1ADRB3ADRB1ADRB2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10036359-A | — | — | None | — | — | JP | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| JP-H1036359-A | PRODUCTION OF 5-(3-CHLOROPHENYL)-3-(2-(3,4-DIMETHOXYPHENYL)-1-METHYLETHYL)-2-OXAZOLIDINONE | SUMITOMO CHEM CO LTD | 1998-02-10 | — | — | JP | disclosed |