Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 9/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 9/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCND2 | Q9NZV8 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204055 | 0.81 | KCNA5 (0.69) | KCNA5SCN5ASLC6A4ALDH1A1TSHR | |
| SCHEMBL1762462 | 0.81 | KCNA5 (0.69) | KCNA5SCN5ASLC6A4ALDH1A1TSHR | |
| SCHEMBL2625038 | 0.81 | KCNA5 (0.69) | KCNA5SCN5ASLC6A4ALDH1A1TSHR | |
| SCHEMBL1762344 | 0.81 | KCNA5 (0.69) | KCNA5SCN5ASLC6A4ALDH1A1TSHR | |
| SCHEMBL12810299 | 0.77 | KCNA5 (0.46) | KCNA5SCN5ASLC6A4KCND2KCNH2 | |
| SCHEMBL14288312 | 0.76 | SLC6A4 (0.62) | KCNA5SCN5AL3MBTL1SLC6A4KCND2 | |
| SCHEMBL2624893 | 0.76 | SLC6A4 (0.62) | KCNA5SCN5AL3MBTL1SLC6A4KCND2 | |
| Hydrochloric Acid SCHEMBL2479603 | 0.75 | KCNA5 (0.62) | KCNA5SCN5AL3MBTL1SLC6A4KCND2 | |
| SCHEMBL4018701 | 0.74 | SLC6A4 (0.57) | KCNA5SCN5ASLC6A4KCND2KCNH2 | |
| SCHEMBL7871969 | 0.74 | KCNA5 (0.46) | KCNA5SCN5ASLC6A4KCND2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000047547-A2 | CYCLOALKYL AMINE COMPOUNDS AND USES THEREOF | NORTRAN PHARMACEUTICALS INC. (CA) | 2000-08-17 | — | — | WO | disclosed |