Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | NAT1 | P18440 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194151 | 1.00 | IGF1R (0.63) | IGF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8187541 | 0.76 | IGF1R (0.78) | IGF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8187544 | 0.76 | IGF1R (0.78) | IGF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8173537 | 0.75 | GSK3B (0.59) | ALDH1A1MEN1KMT2ATDP1PIM1 | |
| SCHEMBL8173541 | 0.75 | GSK3B (0.59) | ALDH1A1MEN1KMT2ATDP1PIM1 | |
| SCHEMBL8172009 | 0.75 | PDE4B (0.46) | IGF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8172007 | 0.75 | PDE4B (0.46) | IGF1RALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8192000 | 0.74 | NAT1 (0.74) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8192006 | 0.74 | NAT1 (0.74) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8189590 | 0.73 | TDP1 (0.70) | IGF1RALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |