Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 3/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192006 | 1.00 | NAT1 (0.74) | NAT1PDE4BGSK3BCA2MAPT | |
| SCHEMBL8309670 | 0.85 | NAT1 (1.00) | NAT1PDE4BGSK3BCA2PTP4A3 | |
| SCHEMBL8309671 | 0.85 | NAT1 (1.00) | NAT1PDE4BGSK3BCA2PTP4A3 | |
| SCHEMBL8173541 | 0.80 | GSK3B (0.59) | NAT1PDE4BGSK3BKMT2ATDP1 | |
| SCHEMBL8173537 | 0.80 | GSK3B (0.59) | NAT1PDE4BGSK3BKMT2ATDP1 | |
| SCHEMBL18103028 | 0.78 | NAT1 (0.85) | NAT1PDE4BGSK3BCA2KMT2A | |
| SCHEMBL8177704 | 0.76 | TDP1 (0.55) | NAT1PDE4BGSK3BMAPTKMT2A | |
| SCHEMBL8177697 | 0.76 | TDP1 (0.55) | NAT1PDE4BGSK3BMAPTKMT2A | |
| SCHEMBL19999112 | 0.76 | NAT1 (0.81) | NAT1PDE4BGSK3BCA2MAPT | |
| SCHEMBL8194152 | 0.74 | IGF1R (0.63) | NAT1PDE4BGSK3BMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018748-A1 | RHODANINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |