⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14741222 | 0.98 | EGLN1 (0.37) | — | |
| SCHEMBL15049363 | 0.78 | — | — | |
| SCHEMBL15049364 | 0.78 | — | — | |
| SCHEMBL27712435 | 0.78 | — | — | |
| SCHEMBL1017667 | 0.78 | — | — | |
| SCHEMBL9234298 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL1017781 | 0.76 | — | — | |
| SCHEMBL29434696 | 0.76 | — | — | |
| SCHEMBL31025958 | 0.71 | — | — | |
| SCHEMBL6281766 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497626-B2 | Variant dihydrodipicolinate reductase polypeptide and method of producing L-threonine using the same | CJ CHEILJEDANG CORPORATION (KR) | 2025-12-16 | — | — | US | claimed |
| WO-2025061082-A1 | METHOD FOR PRODUCING SPERMIDINE | 西安卓虹超源生物科技有限公司 | 2025-03-27 | — | — | WO | claimed |
| CN-111770993-B | Modulation of CSR systems to produce lysine and lysine-derived products | 上海凯赛生物技术股份有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118006528-A | Genetically engineered bacterium for producing tetrahydropyrimidine, preparation method and application | 台州市益善生物技术有限公司 | 2024-05-10 | — | — | CN | claimed |
| EP-4361268-A1 | MDH GENE-BASED POLYNUCLEOTIDE HAVING PROMOTER ACTIVITY AND USE THEREOF | Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences (CN) | 2024-05-01 | — | — | EP | claimed |
| US-20240084314-A1 | MDH GENE-BASED POLYNUCLEOTIDE HAVING PROMOTER ACTIVITY AND USE THEREOF | TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2024-03-14 | — | — | US | claimed |
| US-11781163-B2 | Reducing the accumulation of imines/enamines for the production of amino acids or amino acid-derived products | CATHAY BIOTECH INC. (CN) | 2023-10-10 | — | — | US | claimed |
| CN-116554236-A | Cationic rare earth doped aluminum oxide cluster compound, and macro preparation method and application thereof | 闽都创新实验室 | 2023-08-08 | — | — | CN | claimed |
| CN-111406104-B | Reduction of accumulation of imine/enamine for production of amino acid or amino acid derivative products | 上海凯赛生物技术股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| EP-4202046-A1 | POLYNUCLEOTIDE HAVING PROMOTER ACTIVITY AND APPLICATION OF POLYNUCLEOTIDE IN PRODUCING AMINO ACID | Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences (CN) | 2023-06-28 | — | — | EP | claimed |
| EP-0288758-B1 | DIHYDROPYRIDINAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES | BAYER AG (DE) | 1991-08-14 | — | — | EP | claimed |
| US-4994461-A | Vasodilators; treating cardiovascular disorders | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1991-02-19 | — | — | US | claimed |
| EP-0225574-B1 | NOVEL 1,4-DIHYDROPYRIDINES CONTAINING FLUORINE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1990-05-16 | — | — | EP | claimed |
| CN-1041758-A | The preparation of 4-aryl dihydropyridine acid amides | BAYER AG (DE) | 1990-05-02 | — | — | CN | claimed |
| CN-1039583-A | 1,4-dihydropyridine threonine derivatives, preparation method, intermediate and medicinal application | BAYER AG (DE) | 1990-02-14 | — | — | CN | claimed |
| CN-88101927-A | Dihydropyridine amides, its preparation method and application pharmaceutically | — | 1988-11-16 | — | — | CN | claimed |
| CN-86108499-A | 1 of novel fluorine, 4-dihydropyridine compounds and their preparation method and as the purposes of medicine | — | 1987-07-15 | — | — | CN | claimed |
| EP-0078191-B1 | COLLAGEN INHIBITING COMPOSITIONS AND PROCESSES FOR MANUFACTURING AND USING THE SAME | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1986-09-03 | — | — | EP | claimed |
| US-4428939-A | POLYMERIC HYDROXYPROLINE FOR REDUCTION OF SCAR TISSUE | COLLEGE OF MEDICINE AND DENTISTRY OF NEW JERSEY | 1984-01-31 | — | — | US | claimed |
| EP-0078191-A2 | Collagen inhibiting compositions and processes for manufacturing and using the same | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1983-05-04 | — | — | EP | claimed |