Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197788 | 0.81 | CHRM1 (0.41) | CHRM1ACACBPDGFRBPDGFRACYP19A1 | |
| SCHEMBL8183402 | 0.76 | CHRM1 (0.37) | CHRM1PDGFRBPDGFRA | |
| SCHEMBL6784661 | 0.75 | CHRM1 (0.58) | CHRM1 | |
| SCHEMBL8198118 | 0.74 | PDGFRB (0.34) | PDGFRBPDGFRA | |
| SCHEMBL8196587 | 0.72 | ALDH1A1 (0.40) | CHRM1CYP19A1 | |
| SCHEMBL8196015 | 0.71 | MEN1 (0.32) | CHRM1 | |
| SCHEMBL7885725 | 0.71 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL6989733 | 0.71 | CHRM1 (0.33) | CHRM1CDK2 | |
| SCHEMBL8191689 | 0.71 | CHRM1 (0.40) | CHRM1PDGFRBPDGFRACYP19A1 | |
| SCHEMBL8193676 | 0.70 | CHRM1 (0.33) | CHRM1ACACBPDGFRBPDGFRACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124312-A | ACTIVE DRUG FOR TREATING ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2000-09-26 | — | — | US | claimed |