Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197634 | 0.93 | KMT2A (0.38) | EGFRFGFR1 | |
| SCHEMBL8199806 | 0.90 | S1PR4 (0.41) | — | |
| SCHEMBL8202256 | 0.89 | S1PR4 (0.39) | EGFRFGFR1 | |
| SCHEMBL8197620 | 0.89 | PKM (0.45) | — | |
| SCHEMBL8201679 | 0.88 | S1PR4 (0.42) | — | |
| SCHEMBL8189218 | 0.85 | S1PR4 (0.47) | — | |
| SCHEMBL8196631 | 0.83 | S1PR4 (0.42) | — | |
| SCHEMBL8189242 | 0.82 | S1PR4 (0.40) | — | |
| SCHEMBL8196653 | 0.80 | MAPT (0.44) | — | |
| SCHEMBL9162732 | 0.77 | EGFR (0.39) | EGFRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36832-E | AN ANTICHOLESTEROL AGENT TREATING HYPERCHOLESTEROLEMIA | NIHON NOHYAKU CO., LTD (JP) | 2000-08-22 | — | — | US | disclosed |
| US-5464863-A | Anticholesterol agents | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0613894-A1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |