Morpholine

Morpholine

SCHEMBL8196429

C1COCCN1.CCC(N)OC(=O)C(C)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL4337799 0.84 MEN1 (0.37) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL4170974 0.79 CYP3A4 (0.43) MEN1KMT2AKDM4EGAACYP2C9
Dimethylamine SCHEMBL1139784 0.77 METAP2 (0.30)
Morpholine SCHEMBL8031245 0.76 GAA (0.35) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL28604861 0.72 MEN1 (0.50) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL1257513 0.70 TP53 (0.50) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL29244293 0.70 MEN1 (0.42) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL16445982 0.69 MEN1 (0.46) MEN1KMT2AKDM4EGAACYP2C9
Morpholine SCHEMBL27745084 0.69 MEN1 (0.46) MEN1KMT2AKDM4EGAACYP2C9
Serine SCHEMBL27869053 0.69 SLC7A5 (0.36) MEN1KMT2AKDM4EGAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500601-B1 ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES SUN CHEMICAL CORP (US) 2021-07-28 EP disclosed
US-20210214561-A1 ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES SUN CHEMICAL CORPORATION (US) 2021-07-15 US disclosed
EP-3500601-A1 ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES Sun Chemical Corporation (US) 2019-06-26 EP disclosed
WO-2018035325-A1 ENCAPSULATED MATERIALS WITH IMPROVED PROPERTIES SUN CHEMICAL CORPORATION (US) 2018-02-22 WO disclosed
CN-1678282-A Compositions of anionic polymeric rheology modifiers and cationic materials NOVEON IP HOLDINGS CORP (US) 2005-10-05 CN disclosed
US-6165454-A Stabilized hair care products COLGATE-PALMOLIVE COMPANY (US) 2000-12-26 US disclosed
EP-1014917-A1 STABILIZED HAIR CARE PRODUCTS Colgate-Palmolive Company (US) 2000-07-05 EP disclosed
WO-1999013837-A1 STABILIZED HAIR CARE PRODUCTS COLGATE-PALMOLIVE COMPANY (US) 1999-03-25 WO disclosed