Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.49 |
| ▸ | FNTA | P49354 | 7/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14476244 | 0.91 | CYP11B1 (0.58) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL14476248 | 0.89 | CYP11B1 (0.57) | CYP11B1CYP11B2FNTAPGGT1BFNTB | |
| SCHEMBL8134371 | 0.87 | CYP11B1 (0.62) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL8187875 | 0.84 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAPGGT1BFNTB | |
| SCHEMBL14476617 | 0.78 | FNTA (0.51) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| Hydrochloric Acid SCHEMBL15654401 | 0.77 | FNTA (0.50) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL7983220 | 0.77 | CYP11B1 (0.62) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL5935193 | 0.75 | CYP11B1 (0.63) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL8133106 | 0.75 | CYP11B1 (0.63) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL14476621 | 0.74 | CCR9 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000075135-A1 | BIARYL INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-12-14 | — | — | WO | disclosed |