Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.57 |
| ▸ | FNTA | P49354 | 8/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187875 | 0.94 | CYP11B1 (0.56) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL8196462 | 0.89 | CYP11B1 (0.49) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL14476617 | 0.87 | FNTA (0.51) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| Hydrochloric Acid SCHEMBL15654401 | 0.86 | FNTA (0.50) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL14476246 | 0.83 | FNTA (0.48) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL14476722 | 0.80 | CYP11B1 (0.55) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL5891741 | 0.79 | CYP11B1 (0.58) | CYP11B1CYP11B2FNTAPGGT1BKIF11 | |
| SCHEMBL15654239 | 0.78 | CCR9 (0.47) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| SCHEMBL14476619 | 0.78 | CYP11B1 (0.47) | CYP11B1CYP11B2FNTAPGGT1BIDO1 | |
| Hydrochloric Acid SCHEMBL8227737 | 0.78 | CYP11B1 (0.57) | CYP11B1CYP11B2FNTAPGGT1BKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2014-06-19 | — | — | US | disclosed |
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES (CN) | 2014-06-19 | — | — | US | disclosed |
| EP-2725024-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2014-04-30 | — | — | EP | disclosed |
| WO-2013000267-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 中国科学院上海药物研究所 (CN) | 2013-01-03 | — | — | WO | disclosed |
| WO-2013000108-A1 | AZOLE HETEROCYLIC COMPOUNDS, PREPARATION METHODS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 中国科学院上海药物研究所 (CN) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171431-A1 | AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | PLA2G5, LTA4H, PLA2G4A | CYP11B1 42/4885CYP11B2 41/4885FNTA 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.