SCHEMBL819667

SCHEMBL819667

Nc1ccccc1Nc1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
HSD17B10 Q99714 4/20 0.59
HPGD P15428 3/20 0.59
TSHR P16473 3/20 0.59
CYP3A4 P08684 2/20 0.59
CDC25B P30305 2/20 0.59
TP53 P04637 2/20 0.59
ALOX15 P16050 2/20 0.59
ATM Q13315 1/20 0.59
KEAP1 Q14145 1/20 0.58
KDM1A O60341 1/20 0.55
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
MAPK14 Q16539 1/20 0.53
MAPT P10636 4/20 0.52
KDM4E B2RXH2 3/20 0.52
GAA P10253 3/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28182734 0.98 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL49213 0.87 HSD17B10 (0.74) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL1921580 0.84 HSD17B10 (0.71) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL8500339 0.84 HSD17B10 (0.71) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Ammonia Solution, Strong SCHEMBL11586421 0.84 HSD17B10 (0.71) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL11793098 0.83 EGFR (0.54) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL2677107 0.82 MAPT (0.71) ALDH1A1HSD17B10HPGDCYP3A4TP53
SCHEMBL28097852 0.81 CDC25B (0.79) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL7142449 0.79 HSD17B10 (0.53) ALDH1A1HSD17B10HPGDTSHRCYP3A4
SCHEMBL6796333 0.77 EGFR (0.51) ALDH1A1HSD17B10HPGDTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10190070-B2 Multiple-function dispersant graft polymer CASTROL LIMITED (GB) 2019-01-29 US claimed
CN-102648217-B Low molecular weight polymers of multifunctional multiple graft monomers CASTROL LTD. (GB) 2015-11-25 CN claimed
US-8703873-B2 Multiple function graft polymer CASTROL LIMITED (GB) 2014-04-22 US claimed
CN-101166771-B Multiple-function dispersant graft polymer CASTROL LTD 2013-07-03 CN claimed
EP-2552977-A1 MULTIPLE FUNCTION GRAFT POLYMER Castrol Limited (GB) 2013-02-06 EP claimed
EP-1968955-B1 DIAROMATIC AMINE DERIVATIVES AS ANTIOXIDANTS CHEMTURA CORP (US) 2013-02-06 EP claimed
CN-102822216-A Multifunctional graft polymers CASTROL LTD 2012-12-12 CN claimed
EP-2501726-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER Castrol Limited (GB) 2012-09-26 EP claimed
CN-102648217-A Low molecular weight polymers of multifunctional multiple graft monomers CASTROL LTD 2012-08-22 CN claimed
US-20110287992-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER CASTROL LIMITED (US) 2011-11-24 US claimed
EP-1574559-A1 Dispersants for lubricants and fuels Afton Chemical Corporation (US) 2005-09-14 EP claimed
US-6255387-B1 COMPRISING ETHYLENE-PROPYLENE COPOLYMER FUNCTIONALIZED WITH A GRAFTING MONOMER AND REACTED WITH A COMPOUND CONTAINING AMINE, HYDROXYL OR MERCAPTO MOIETIES DURING PROCESSING UNDER CONCURRENT HIGH BLENDING AND SHEARING ENERGY CONDITIONS ETHYL ADDITIVES CORPORATION 2001-07-03 US claimed
US-5837773-A ETHYLENE-PROPYLENE COPOLYMER DSM COPOLYMER, INC. (US) 1998-11-17 US claimed
CN-1172846-A Branched polyolefin polymers as additives in fuel and lubricating oil compositions DSM COPOLYMER INC (US) 1998-02-11 CN claimed
US-5651927-A MOLECULAR WEIGHT REDUCTION WITH PEROXIDE, GRAFTING WITH MALEIC ANHYDRIDE, IMIDIZATION EXXON CHEMICAL PATENTS INC. (US) 1997-07-29 US claimed
US-5308523-A Butylene-ethylene-styrene terpolymer block copolymer TEXACO INC. (US) 1994-05-03 US claimed
EP-0446510-B1 Stable middle distillate fuel-oil compositions TEXACO DEVELOPMENT CORP (US) 1993-10-20 EP claimed
US-5112508-A Maleinized Olefin Interpolymer reacted with an N-Naphthylphenylenediamine TEXACO, INC. (US) 1992-05-12 US claimed
EP-0446510-A1 Stable middle distillate fuel-oil compositions TEXACO DEVELOPMENT CORPORATION (US) 1991-09-18 EP claimed
US-4919683-A CONTAINING AS STORAGE STABILIZER A COPOLYMER GRAFTED WITH AN AROMATIC POLYAMINE SUCCINIMIDE TEXACO INC. (US) 1990-04-24 US claimed