SCHEMBL819674

SCHEMBL819674

CCCCCCc1ccsc1C#N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
LIPG Q9Y5X9 1/20 0.39
TYR P14679 2/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
MEN1 O00255 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CYSLTR2 Q9NS75 2/20 0.35
CYSLTR1 Q9Y271 2/20 0.35
GPR35 Q9HC97 1/20 0.35
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5948584 1.00 TSHR (0.42) TSHRHSD17B10LIPGTYRTP53
SCHEMBL978866 1.00 TSHR (0.42) TSHRHSD17B10LIPGTYRTP53
SCHEMBL2305264 0.93 HSD17B10 (0.37) TSHRHSD17B10LIPGTYRMEN1
SCHEMBL6811876 0.85 KDM4E (0.36) HSD17B10MEN1MAPTKMT2AKDM4E
SCHEMBL28372081 0.83 LIPG (0.39) TSHRHSD17B10LIPGTYRTP53
SCHEMBL28367934 0.83 LIPG (0.39) TSHRHSD17B10LIPGTYRTP53
SCHEMBL4471052 0.83 LIPG (0.39) TSHRHSD17B10LIPGTYRTP53
SCHEMBL28367976 0.83 LIPG (0.39) TSHRHSD17B10LIPGTYRTP53
SCHEMBL28372084 0.83 LIPG (0.39) TSHRHSD17B10LIPGTYRTP53
SCHEMBL7473682 0.83 LIPG (0.39) TSHRHSD17B10LIPGTYRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673183-B2 Tetrazine monomers and copolymers for use in organic electronic devices NATIONAL RESEARCH COUNCIL OF CANADA 2014-03-18 US disclosed
US-8313978-B2 Organic semiconductor copolymers containing oligothiophene and n-type heteroaromatic units SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-11-20 US disclosed
US-20120077949-A1 Organic semiconductor copolymers containing oligothiophene and n-type heteroaromatic units LEE BANG LIN (KR) 2012-03-29 US disclosed
US-20120007026-A1 TETRAZINE MONOMERS AND COPOLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-01-12 US disclosed
US-8053764-B2 pi-conjugated copolymers comprising /N-heterocycle/ polymers, used in electronics, such as for channel layer materials in thin film transistors SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-11-08 US disclosed
US-20080224130-A1 ORGANIC SEMICONDUCTOR COPOLYMERS CONTAINING OLIGOTHIOPHENE AND n-TYPE HETEROAROMATIC UNITS SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-09-18 US disclosed
EP-1615237-B1 Organic semiconductor copolymers containing oligothiophene and n-type heteroaromatic units SAMSUNG ELECTRONICS CO LTD (KR) 2008-09-10 EP disclosed
US-7368510-B2 Organic semiconductor copolymers containing oligothiophene and n-type heteroaromatic units SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-05-06 US disclosed
US-20060006379-A1 Organic semiconductor copolymers containing oligothiophene and n-type heteroaromatic units SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-01-12 US disclosed
EP-1615237-A1 Organic semiconductor copolymers containing oligothiophene and n-type heteroaromatic units Samsung Electronics Co., Ltd (KR) 2006-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120007026-A1 TETRAZINE MONOMERS AND COPOLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES CCNE1, CCNE2, WEE1 TSHR 2462/4885HSD17B10 2481/4885LIPG 4626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.