Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL819598 | 0.79 | MEN1 (0.39) | TSHRMEN1KMT2ATDP1 | |
| SCHEMBL27388323 | 0.73 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL708310 | 0.73 | MEN1 (0.50) | MEN1KMT2ATDP1 | |
| SCHEMBL11676897 | 0.72 | — | — | |
| Alcohol SCHEMBL8234061 | 0.69 | — | — | |
| Alcohol SCHEMBL28233814 | 0.69 | — | — | |
| Alcohol SCHEMBL6910520 | 0.68 | TSHR (1.00) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| Alcohol SCHEMBL17770701 | 0.68 | — | — | |
| Alcohol SCHEMBL2464657 | 0.68 | TSHR (1.00) | ALDH1A1TSHRMEN1KMT2ATDP1 | |
| Alcohol SCHEMBL9461084 | 0.68 | TSHR (1.00) | ALDH1A1TSHRMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518618-B2 | Electrophotographic photoconductor, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2013-08-27 | — | — | US | disclosed |
| US-20120009513-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2012-01-12 | — | — | US | disclosed |