Cinnoline

Cinnoline

SCHEMBL8197

c1ccc2nnccc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.48
HPGD P15428 2/20 0.48
GLA P06280 1/20 0.48
ACHE P22303 1/20 0.48
NCF1 P14598 3/20 0.41
CYP1A2 P05177 2/20 0.41
NOS2 P35228 1/20 0.41
BACE1 P56817 1/20 0.41
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
NQO2 P16083 1/20 0.40
KDM4E B2RXH2 3/20 0.39
NPC1 O15118 1/20 0.39
CYP3A4 P08684 1/20 0.39
AR P10275 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinnoline SCHEMBL29367576 1.00 ALDH1A1 (0.50) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL29388384 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL27880915 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL27701648 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL29067411 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL29184286 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL8589764 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL29733325 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
SCHEMBL3205273 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE
Cinnoline SCHEMBL18209355 0.97 ALDH1A1 (0.48) ALDH1A1MAPTHPGDGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 63001 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146168-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2026-05-28 US claimed
CN-122080076-A Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device 2026-05-26 CN claimed
CN-122036623-A Method for photochemically synthesizing benzo [ c ] cinnolines from azo compounds 山东金科力电源科技有限公司 2026-05-15 CN claimed
US-12624055-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-05-12 US claimed
US-20260130106-A1 PHOTOELECTRIC DEVICE AND PREPARATION METHOD THEREFOR TCL TECHNOLOGY GROUP CORPORATION (CN) 2026-05-07 US claimed
US-12616690-B2 Specific AKT3 activator and uses thereof AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) 2026-05-05 US claimed
US-20260115176-A1 ALLOSTERIC MODULATORS OF CANNABINOID RECEPTORS AND METHODS OF TREATING NEUROPATHIC PAIN UNIV LELAND STANFORD JUNIOR (US) 2026-04-30 US claimed
EP-4727939-A1 5-(CINNOLIN-6-YL)THIAZOLE COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS Prothena Biosciences Limited (IE) 2026-04-22 EP claimed
EP-4720041-A2 N-(1H-INDOL-2-YL)METHYL)-4-ETHYNYL-PICOLINAMIDE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER Allorion Therapeutics Inc (US) 2026-04-08 EP claimed
US-12593378-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-03-31 US claimed
EP-0002573-A1 Information storage material International Business Machines Corporation (US) 1979-06-27 EP claimed
US-4158890-A Frequency selective optical data storage system INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-06-19 US claimed
US-4156724-A N-acylamino-alpha-arylacetamido cephalosporins and antibacterial compositions and methods containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-05-29 US claimed
US-4125613-A INSECTICIDE, MITICIDE SHELL OIL COMPANY (US) 1978-11-14 US claimed
US-4125611-A MICROBIOCIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-11-14 US claimed
US-4110237-A Compositions containing a diazine and a halogen compound for catalyzing copper etching solutions Tokai Denka Kabushiki Kaisha (JP) 1978-08-29 US claimed
US-4085098-A Azo dyes containing a heterocyclic ring having a quaternized nitrogen atom and at least one optionally substituted phenoxyalkyl or naphthyloxyalkyl substituent SANDOZ LTD. (CH) 1978-04-18 US claimed
US-4005075-A Penicillins and their preparation SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-25 US claimed
US-3959100-A OPACIFIER SCM CORPORATION (US) 1976-05-25 US claimed
US-3936332-A DIAZINE, PEROXYSULFATE, HALOGEN COMPOUND TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) 1976-02-03 US claimed