Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.50 |
| ▸ | RARB | P10826 | 9/20 | 0.50 |
| ▸ | RARG | P13631 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19034088 | 0.87 | RARB (0.62) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL4309215 | 0.84 | RARA (0.50) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL16913398 | 0.84 | RARB (0.56) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL7217365 | 0.84 | RARA (0.50) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL4373673 | 0.79 | RARB (0.58) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL8293245 | 0.76 | RARA (0.47) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL9817648 | 0.75 | CYP3A4 (0.76) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL9188112 | 0.75 | RARA (0.49) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL13708653 | 0.75 | RARA (0.46) | RARARARBRARGCYP3A4CYP26A1 | |
| SCHEMBL9054284 | 0.75 | RARA (0.46) | RARARARBRARGCYP3A4CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003569-A2 | STERILE BIOERODIBLE IMPLANT DEVICE WITH IMPROVED BIOCOMPATABILITY AND METHOD | Allergan Sales, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007418-A2 | STERILE BIOERODIBLE IMPLANT DEVICE WITH IMPROVED BIOCOMPATABILITY AND METHOD | ALLERGAN SALES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |