Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818058 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HPGDTDP1LMNA | |
| SCHEMBL818752 | 0.83 | TSHR (0.40) | ALDH1A1KDM4EMAPTHPGDTDP1 | |
| SCHEMBL819627 | 0.83 | TSHR (0.42) | ALDH1A1KDM4EMAPTHSD17B10LMNA | |
| SCHEMBL819131 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTHSD17B10LMNA | |
| SCHEMBL818660 | 0.82 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTHSD17B10HTT | |
| SCHEMBL28369299 | 0.81 | MAPT (0.43) | ALDH1A1GAAKMT2AKDM4EMAPT | |
| SCHEMBL819433 | 0.78 | GAA (0.40) | ALDH1A1GAAKMT2AKDM4EMAPT | |
| SCHEMBL818754 | 0.77 | TSHR (0.38) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL819340 | 0.77 | TLR4 (0.39) | ALDH1A1GAAKMT2AKDM4EMAPT | |
| SCHEMBL10632667 | 0.76 | MAPT (0.44) | ALDH1A1GAAKMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236908-B2 | Components and catalysts for the polymerization of olefins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20110269927-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-03 | — | — | US | disclosed |