Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873473 | 0.80 | GRM5 (0.58) | GRM5FFAR1PTPN1PTGESCES2 | |
| SCHEMBL28722711 | 0.79 | GABRP (0.44) | FFAR1PTGESCES2MGLLNR1H2 | |
| SCHEMBL8006286 | 0.77 | GRM5 (0.53) | GRM5FFAR1PTPN1PTGESHTR2A | |
| SCHEMBL8217128 | 0.75 | GRM5 (0.49) | GRM5FFAR1PTGES | |
| SCHEMBL27821982 | 0.74 | PTPN1 (0.60) | GRM5FFAR1PTPN1PTGESPTGDR2 | |
| SCHEMBL17036543 | 0.74 | GRM5 (0.50) | GRM5FFAR1PTPN1PTGESHTR2A | |
| SCHEMBL8186068 | 0.74 | KCNH2 (0.50) | GRM5PTGESPNMTPTGDR2 | |
| SCHEMBL11459465 | 0.74 | HSD17B2 (0.45) | FFAR1 | |
| SCHEMBL4472156 | 0.73 | FFAR1 (0.52) | GRM5FFAR1PTPN1PTGESNPSR1 | |
| SCHEMBL15873985 | 0.73 | KDM4E (0.43) | HTR2AHTR2CHTR2BNPSR1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000024742-A1 | PYRAZOLOPYRIDINE AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-04 | — | — | WO | disclosed |