Sugi Predict

Sugi Predict / Compounds / SCHEMBL81977

SCHEMBL81977

SCHEMBL81977

O=C(O)/C=C\C(=O)NCCCCCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 1/20 0.59
▸ ADRA1A P35348 1/20 0.55
▸ ALDH1A1 P00352 3/20 0.53
▸ POLB P06746 2/20 0.52
▸ TAAR1 Q96RJ0 2/20 0.51
▸ MAPK1 P28482 1/20 0.49
▸ EPHX2 P34913 7/20 0.46
▸ LMNA P02545 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ NFKB1 P19838 1/20 0.46
▸ PMP22 Q01453 1/20 0.46
▸ PLA2G2A P14555 1/20 0.46
▸ HDAC3 O15379 1/20 0.45
▸ HDAC4 P56524 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ HDAC7 Q8WUI4 1/20 0.45
▸ HDAC2 Q92769 1/20 0.45
▸ HDAC10 Q969S8 1/20 0.45
▸ HDAC11 Q96DB2 1/20 0.45
▸ HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11133362 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL11133946 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL11141321 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL515857 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL11137045 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL24686717 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL8779381 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL8779450 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL8779440 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1
SCHEMBL11136996 1.00 PRMT1 (0.59) PRMT1ADRA1AALDH1A1POLBTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113718256-B Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2022-11-11 — — CN claimed
CN-113718256-A Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2021-11-30 — — CN claimed
US-4320173-A REINFORCEMENT AND ADHESIVES FOR VULCANIZED PRODUCTS MONSANTO COMPANY (US) 1982-03-16 — — US claimed
US-12115226-B2 Linker containing arylnitro, antibody-drug conjugate containing linker and use of linker ACADEMY OF MILITARY MEDICAL SCIENCES (CN) 2024-10-15 — — US disclosed
EP-3838893-B1 LINKER, ANTIBODY-DRUG CONJUGATE INCLUDING SAME, AND USE THEREOF ACAD OF MILITARY MEDICAL SCIENCES (CN) 2023-04-19 — — EP disclosed
CN-113718256-B Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2022-11-11 — — CN disclosed
CN-112601556-B Linker containing aromatic nitro group, antibody conjugate drug containing linker and application of linker 中国人民解放军军事科学院军事医学研究院 2022-08-09 — — CN disclosed
CN-113718256-A Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2021-11-30 — — CN disclosed
US-20210205464-A1 Linker Containing Arylnitro, Antibody-Drug Conjugate Containing Linker and Use of Linker ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) 2021-07-08 — — US disclosed
US-20210205464-A1 Linker Containing Arylnitro, Antibody-Drug Conjugate Containing Linker and Use of Linker ZHEJIANG YANGSHENGTANG INSTITUTE OF NATURAL MEDICATION CO., LTD. (CN) 2021-07-08 — — US disclosed
EP-3845251-A1 LINKER CONTAINING ARYLNITRO, ANTIBODY-DRUG CONJUGATE CONTAINING LINKER AND USE OF LINKER Academy of Military Medical Sciences (CN) 2021-07-07 — — EP disclosed
EP-0888389-A1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS SurModics, Inc. (US) 1999-01-07 — — EP disclosed
WO-1997034935-A1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS BSI CORPORATION (US) 1997-09-25 — — WO disclosed
EP-0665020-A2 Method for preparing thioether conjugates BRISTOL-MYERS SQUIBB COMPANY (US) 1995-08-02 — — EP disclosed
EP-0080451-B1 METHOD AND COMPOSITION FOR DIENE RUBBER TREATMENT MONSANTO COMPANY (US) 1985-09-18 — — EP disclosed
US-4433114-A SULFUR OR ORGANOSULFUR COMPOUNDS, MALEAMIC ACID OR DERIVATIVES, TACKINESS, GREEN STRENGTH MONSANTO COMPANY (US) 1984-02-21 — — US disclosed
EP-0080451-A1 Method and composition for diene rubber treatment MONSANTO COMPANY (US) 1983-06-01 — — EP disclosed
US-4374956-A METAL ADHESIVES MONSANTO COMPANY (US) 1983-02-22 — — US disclosed
US-4350740-A SUBSTITUTED MALEAMIC ACID MODIFIER; ADHESION TO METALS MONSANTO COMPANY (US) 1982-09-21 — — US disclosed
US-4320173-A REINFORCEMENT AND ADHESIVES FOR VULCANIZED PRODUCTS MONSANTO COMPANY (US) 1982-03-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210205464-A1 Linker Containing Arylnitro, Antibody-Drug Conjugate Containing Linker and Use of Linker BCR, FCGRT, ERBB2 PRMT1 3824/4885ADRA1A 3077/4885ALDH1A1 962/4885
US-12115226-B2 Linker containing arylnitro, antibody-drug conjugate containing linker and use of linker BCR, FCGR2A, FCGRT PRMT1 3835/4885ADRA1A 3222/4885ALDH1A1 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.