Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133362 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL11133946 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL11141321 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL515857 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL81977 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL11137045 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL24686717 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL8779450 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL8779440 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 | |
| SCHEMBL11136996 | 1.00 | PRMT1 (0.59) | PRMT1ADRA1AALDH1A1POLBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507348-B1 | Superoxide dismutase derivatives | KURARAY CO (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5360914-A | Intermediates for superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5238837-A | Antiinflammatory agents, antiulcer agents | KURARAY CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0507348-A2 | Superoxide dismutase derivatives | KURARAY CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |