Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | RARG | P13631 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | GOT1 | P17174 | 1/20 | 0.50 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29535143 | 0.98 | RARA (0.51) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL178217 | 0.98 | RARA (0.51) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL28281248 | 0.97 | HDAC11 (0.53) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL566075 | 0.87 | HDAC11 (0.62) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL3309247 | 0.86 | HDAC11 (0.43) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL27650736 | 0.85 | TDP1 (0.42) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL1196452 | 0.85 | RARB (0.67) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL30076502 | 0.83 | HDAC11 (0.40) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL30076513 | 0.83 | HDAC11 (0.40) | RARARARBRARGLMNAHDAC11 | |
| SCHEMBL9763614 | 0.82 | RARA (0.49) | RARARARBRARGLMNAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902010-B1 | PROCESS FOR THE PREPARATION OF ADAPALENE AND RELATED COMPOUNDS | MEDICHEM SA (ES) | 2011-11-30 | — | — | EP | claimed |