Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267490 | 0.86 | ABCC9 (0.46) | ABCC9 | |
| SCHEMBL9140628 | 0.86 | ABCC9 (0.46) | ABCC9 | |
| SCHEMBL9140641 | 0.86 | ABCC9 (0.46) | ABCC9 | |
| SCHEMBL8203937 | 0.81 | ABCC9 (0.38) | ABCC9 | |
| SCHEMBL7267578 | 0.76 | ABCC9 (0.42) | DRD3ABCC9KCNA5 | |
| SCHEMBL8090456 | 0.76 | ABCC9 (0.46) | ABCC9 | |
| SCHEMBL7269439 | 0.74 | ABCC9 (0.44) | ABCC9KCNA5 | |
| SCHEMBL8088411 | 0.74 | KDM4E (0.33) | ABCC9KDM4E | |
| SCHEMBL9313794 | 0.74 | ABCC9 (0.44) | ABCC9KCNA5 | |
| SCHEMBL9313807 | 0.74 | ABCC9 (0.44) | ABCC9KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040308-A | Chroman derivatives | MERCK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-21 | — | — | US | disclosed |