Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 11/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198477 | 1.00 | OGA (0.63) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL14426665 | 0.78 | OGA (0.66) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL657716 | 0.78 | OGA (0.66) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL14439290 | 0.78 | OGA (1.00) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL14426666 | 0.78 | OGA (1.00) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL8203562 | 0.77 | OGA (0.64) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL8197445 | 0.77 | OGA (0.64) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL14342859 | 0.73 | OGA (0.59) | OGALMNAGBA1ALDH1A1THRB | |
| SCHEMBL468706 | 0.64 | PYGB (0.67) | — | |
| SCHEMBL7149670 | 0.64 | PYGB (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934325-A4 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | PHARMASSET LTD (US) | 2000-08-16 | — | — | EP | claimed |
| EP-0934325-A1 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | Pharmasset, Ltd. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998015563-A1 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | PHARMASSET, LTD. (US) | 1998-04-16 | — | — | WO | claimed |
| EP-0934325-A4 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | PHARMASSET LTD (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-0934325-A1 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | Pharmasset, Ltd. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015563-A1 | TETRAPHOSPHONATE BICYCLIC TRISANHYDRIDES | PHARMASSET, LTD. (US) | 1998-04-16 | — | — | WO | disclosed |