Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 4/20 | 0.59 |
| ▸ | TACR1 | P25103 | 8/20 | 0.54 |
| ▸ | TACR3 | P29371 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198180 | 1.00 | NMBR (0.59) | NMBRTACR1TACR3 | |
| SCHEMBL9085402 | 0.88 | TACR1 (0.55) | NMBRTACR1TACR3 | |
| SCHEMBL8203051 | 0.82 | TACR1 (0.75) | TACR1TACR3 | |
| SCHEMBL8200376 | 0.82 | TACR1 (0.75) | TACR1TACR3 | |
| SCHEMBL7641918 | 0.82 | TACR1 (0.75) | TACR1TACR3 | |
| SCHEMBL8829903 | 0.82 | NMBR (0.60) | NMBR | |
| SCHEMBL8829899 | 0.82 | NMBR (0.60) | NMBR | |
| SCHEMBL8488187 | 0.81 | NMBR (0.50) | NMBRTACR1 | |
| SCHEMBL1388680 | 0.81 | KMT2A (0.48) | NMBRTACR1 | |
| SCHEMBL9017344 | 0.80 | NMBR (0.60) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | claimed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | claimed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | claimed |
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |