Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.60 |
| ▸ | CCKBR | P32239 | 4/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829899 | 1.00 | NMBR (0.60) | NMBRCCKBRBCHE | |
| SCHEMBL8829876 | 0.84 | CCKBR (0.68) | NMBRCCKBR | |
| SCHEMBL6181070 | 0.84 | NMBR (0.86) | NMBRCCKBR | |
| SCHEMBL8829853 | 0.83 | CCKBR (0.55) | NMBRCCKBR | |
| SCHEMBL6892425 | 0.83 | CCKBR (0.78) | NMBRCCKBR | |
| SCHEMBL8829915 | 0.82 | CCKBR (0.56) | NMBRCCKBR | |
| SCHEMBL8198181 | 0.82 | NMBR (0.59) | NMBR | |
| SCHEMBL8198180 | 0.82 | NMBR (0.59) | NMBR | |
| SCHEMBL9017344 | 0.81 | NMBR (0.60) | NMBR | |
| SCHEMBL9377083 | 0.80 | CCKBR (0.52) | NMBRCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631281-A | COMPOUNDS FOR TREATMENT OF ANXIETY WITH INDOLE AMIDES | WARNER-LAMBERT COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5622983-A | ANTIOBESITY AGENTS, ANTIPSYCHOTIC AGENTS, ANTIULCER AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5580896-A | Treatment of pain and colorectal cancer with dipeptoids of α-substituted Trp-Phe derivatives | WARNER-LAMBERT COMPANY (US) | 1996-12-03 | — | — | US | disclosed |
| US-5278316-A | Indoles | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |