Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612 | 0.82 | GRIK1 (0.35) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL5082914 | 0.82 | GRIK1 (0.35) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL27538085 | 0.79 | CTSK (0.34) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL17871166 | 0.78 | CTSK (0.38) | CTSKKMT2AMEN1GAALMNA | |
| SCHEMBL3745027 | 0.77 | KMT2A (0.39) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL1344808 | 0.77 | KMT2A (0.39) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL3745034 | 0.77 | KMT2A (0.39) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL2076664 | 0.77 | KMT2A (0.39) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL28710632 | 0.77 | KMT2A (0.39) | CTSKKMT2AMEN1GAAAAK1 | |
| SCHEMBL951740 | 0.76 | CTSK (0.37) | CTSKKMT2ALMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049660-A1 | COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999019295-A1 | COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1999-04-22 | — | — | WO | disclosed |