SCHEMBL8198293

SCHEMBL8198293

Cc1ccc(OC(=O)c2ccccc2[N+](=O)[O-])cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.60
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
GAA P10253 2/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
PTK2B Q14289 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
ALDH1A1 P00352 5/20 0.52
MEN1 O00255 3/20 0.52
NPSR1 Q6W5P4 3/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 4/20 0.49
GLA P06280 1/20 0.49
HPGD P15428 2/20 0.48
LMNA P02545 2/20 0.48
TP53 P04637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31588107 0.87 KMT2A (0.71) KMT2ANPC1RAB9ASMN1; SMN2GAA
SCHEMBL17673999 0.87 KMT2A (0.71) KMT2ANPC1RAB9ASMN1; SMN2GAA
SCHEMBL28491071 0.86 KMT2A (0.62) KMT2ASMN1; SMN2GAAALDH1A1MAPT
SCHEMBL9189168 0.85 KMT2A (0.60) KMT2ANPC1RAB9ASMN1; SMN2GAA
SCHEMBL9156951 0.84 KMT2A (0.56) KMT2ANPC1RAB9ASMN1; SMN2GAA
SCHEMBL26343309 0.84 KMT2A (0.61) KMT2ANPC1RAB9ASMN1; SMN2GAA
SCHEMBL208281 0.82 PTK2B (0.70) KMT2APTK2BRXFP1ALDH1A1MEN1
SCHEMBL8386067 0.81 SMN1; SMN2 (0.66) KMT2ANPC1RAB9ASMN1; SMN2GAA
SCHEMBL10983921 0.79 PTK2B (0.66) KMT2APTK2BRXFP1ALDH1A1MEN1
SCHEMBL23086256 0.78 NPC1 (0.51) KMT2ANPC1RAB9ASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4444844-A LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY RICOH CO., LTD. (JP) 1984-04-24 US disclosed