Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.63 |
| ▸ | MMP8 | P22894 | 3/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | ECE1 | P42892 | 6/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28747928 | 0.85 | MMP9 (0.63) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL7677247 | 0.84 | MMP9 (0.74) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL8201151 | 0.83 | MMP9 (0.80) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL8201153 | 0.83 | MMP9 (0.80) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL8850370 | 0.83 | MMP9 (0.80) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL8850751 | 0.82 | MMP9 (0.60) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL8850747 | 0.82 | MMP9 (0.60) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL7064069 | 0.82 | MMP9 (0.68) | MMP9MMP8MMP2MEN1KMT2A | |
| SCHEMBL6431194 | 0.81 | ECE1 (0.79) | MMP9MMP8MMP2ACEECE1 | |
| SCHEMBL1388789 | 0.81 | MMP9 (0.58) | MMP9MMP8MMP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | claimed |
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |