Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18700373 | 1.00 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL20352210 | 0.85 | TSHR (0.38) | ALDH1A1TSHRTDP1CHRM1LMNA | |
| SCHEMBL18113059 | 0.84 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18113057 | 0.82 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL31065466 | 0.81 | MGAM (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL18113184 | 0.81 | MGAM (0.40) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8500057 | 0.79 | TSHR (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1131553 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3077876 | 0.79 | MGAM (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8500054 | 0.79 | TSHR (0.46) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355935-B1 | PYRROLOBENZODIAZEPINE ANTIBODY DRUG CONJUGATES AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2020-10-21 | — | — | EP | disclosed |
| US-10011668-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-07-03 | — | — | US | disclosed |
| US-20180057622-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-03-01 | — | — | US | disclosed |
| US-8536364-B2 | Method for producing sulfur-containing carboxylic acid esters | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-09-17 | — | — | US | disclosed |
| EP-2452933-A1 | Method for producing sulfur-containing carboxylic acid esters | Takasago International Corporation (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-20110282089-A1 | METHOD FOR PRODUCING SULFUR-CONTAINING CARBOXYLIC ACID ESTERS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-11-17 | — | — | US | disclosed |
| US-4454134-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282089-A1 | METHOD FOR PRODUCING SULFUR-CONTAINING CARBOXYLIC ACID ESTERS | CBR3, ALDH18A1, TAS2R3 | MGAM 2847/4885GAA 1742/4885SI 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.