Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADK | P55263 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205716 | 1.00 | LMNA (0.52) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL8199201 | 0.90 | LMNA (0.53) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL7207502 | 0.90 | LMNA (0.53) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL7205777 | 0.88 | LMNA (0.60) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL8184740 | 0.88 | LMNA (0.60) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL7205736 | 0.87 | LMNA (0.54) | LMNAADK | |
| SCHEMBL8184776 | 0.87 | LMNA (0.54) | LMNAADK | |
| SCHEMBL8203607 | 0.86 | LMNA (0.60) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL8203611 | 0.86 | LMNA (0.60) | LMNAADKTSHRMAPTPMP22 | |
| SCHEMBL8193849 | 0.85 | LMNA (0.56) | LMNAADKTSHRMAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | claimed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | claimed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |