Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400350 | 0.82 | USP2 (0.44) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL28398203 | 0.82 | USP2 (0.41) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL27660609 | 0.80 | ATM (0.34) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL22534100 | 0.80 | ATM (0.36) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL16578256 | 0.80 | ALDH1A1 (0.35) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL28830014 | 0.80 | ATM (0.34) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL8224891 | 0.80 | ATM (0.36) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL13475327 | 0.78 | ATM (0.35) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL14628202 | 0.78 | ATM (0.35) | ATMUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL15083263 | 0.77 | ALDH1A1 (0.38) | ATMUSP2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043278-A | FORMULATION COMPRISING MIXTURE OF BETA-LACTAM ANTIBIOTIC AND PERFLUOROLOWERALKYL DERIVATIVE OF AMINO ACID | ISIS INNOVATION LIMITED (GB) | 2000-03-28 | — | — | US | disclosed |