Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818162 | 0.73 | TSHR (0.43) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL820840 | 0.73 | TSHR (0.43) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL27821707 | 0.72 | DRD2 (0.46) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL818648 | 0.72 | TSHR (0.45) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL820255 | 0.72 | DRD2 (0.46) | PREPTSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL820466 | 0.72 | TSHR (0.45) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL5267939 | 0.72 | SPHK2 (0.58) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL809494 | 0.72 | SPHK2 (0.58) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL4602602 | 0.72 | SPHK2 (0.58) | PREPTSHRL3MBTL1KLK7KLK5 | |
| SCHEMBL29599061 | 0.71 | PREP (0.53) | PREPTSHRL3MBTL1KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUITCAL CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288116-A1 | IAP INHIBITORS | XIAP, BIRC5, BIRC7 | PREP 221/4885TSHR 4584/4885L3MBTL1 2036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.