Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | SOD1 | P00441 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485782 | 0.85 | KDM4E (0.43) | MAOBMAOASOD1ALDH1A1KDM4E | |
| SCHEMBL2794233 | 0.81 | MAOB (0.51) | MAOBMAOASOD1ALDH1A1KDM4E | |
| Formaldehyde SCHEMBL27685853 | 0.81 | MAOB (0.51) | MAOBMAOASOD1ALDH1A1KDM4E | |
| SCHEMBL472525 | 0.81 | MAOB (0.55) | MAOBMAOASOD1ALDH1A1KDM4E | |
| SCHEMBL31573499 | 0.81 | MAOB (0.55) | MAOBMAOASOD1ALDH1A1KDM4E | |
| Propionaldehyde SCHEMBL27848593 | 0.80 | MAOB (0.50) | MAOBMAOASOD1ALDH1A1KDM4E | |
| SCHEMBL5251518 | 0.80 | KDM4E (0.52) | MAOBMAOAALDH1A1KDM4ERAB9A | |
| SCHEMBL98467 | 0.79 | KDM4E (0.54) | MAOBALDH1A1KDM4ERAB9ALMNA | |
| SCHEMBL14241526 | 0.78 | MAOB (0.42) | MAOBMAOAKDM4ERAB9A | |
| SCHEMBL27555356 | 0.78 | MAOB (0.51) | MAOBMAOASOD1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280288-A1 | PYRROLE SULFONYL DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 天地恒一制药股份有限公司 | 2023-01-12 | — | — | WO | disclosed |
| EP-0968168-A1 | AROMATIC TETRACYCLIC COMPOUNDS OF THE RETINOID TYPE, METHOD FOR PREPARING AND USE | Centre Europeen de Bioprospective -CEB (FR) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998031654-A1 | AROMATIC TETRACYCLIC COMPOUNDS OF THE RETINOID TYPE, METHOD FOR PREPARING AND USE | CENTRE EUROPEEN DE BIOPROSPECTIVE -CEB- (FR) | 1998-07-23 | — | — | WO | disclosed |
| US-4287209-A | USEFUL AS METABOLIC REGULATORS, AND HERBICIDES | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1981-09-01 | — | — | US | disclosed |
| US-4146385-A | METABOLIC REGULATORS, CARDIOVASCULAR AGENTS, HERBICIDES | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1979-03-27 | — | — | US | disclosed |