Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199273 | 0.85 | MAOB (0.55) | KDM4EMAOBALDH1A1MAOALMNA | |
| SCHEMBL5986464 | 0.82 | LTA4H (0.42) | MAOALMNA | |
| SCHEMBL9317278 | 0.81 | KDM4E (0.49) | KDM4EHSD17B10MAOBALDH1A1LMNA | |
| Propionaldehyde SCHEMBL27848593 | 0.77 | MAOB (0.50) | KDM4EMAOBALDH1A1MAOALMNA | |
| SCHEMBL4195169 | 0.77 | KDM4E (0.44) | KDM4EHSD17B10MAOBALDH1A1LMNA | |
| SCHEMBL6712899 | 0.77 | ALDH1A1 (0.62) | MAOBALDH1A1MAOALMNAMAPT | |
| SCHEMBL5645717 | 0.76 | FFAR1 (0.43) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL12261469 | 0.75 | MAOB (0.47) | KDM4EHSD17B10MAOBALDH1A1LMNA | |
| SCHEMBL5648390 | 0.75 | PPARG (0.44) | KDM4EMAOBALDH1A1MAOALMNA | |
| Ethylene SCHEMBL3645192 | 0.74 | ALDH1A1 (0.59) | MAOBALDH1A1MAOALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142929-A2 | NOVEL PDE4 INHIBITORS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-12-13 | — | — | WO | disclosed |