SCHEMBL819951

SCHEMBL819951

Nc1ccccc1-c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.56
LMNA P02545 3/20 0.56
CCR1 P32246 2/20 0.56
CCR5 P51681 2/20 0.56
CCR8 P51685 2/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56
METAP1 P53582 1/20 0.56
BLM P54132 1/20 0.56
HIF1A Q16665 1/20 0.56
DOHH Q9BU89 1/20 0.56
P4HTM Q9NXG6 1/20 0.56
TDO2 P48775 1/20 0.53
L3MBTL1 Q9Y468 4/20 0.52
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 3/20 0.50
NPC1 O15118 7/20 0.48
RAB9A P51151 5/20 0.48
TP53 P04637 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450625 1.00 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
SCHEMBL3978651 0.87 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4926391 0.85 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30423262 0.85 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
Hydrochloric Acid SCHEMBL15365337 0.84 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL28562697 0.83 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
SCHEMBL858806 0.83 KDM4E (0.72) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1513870 0.82 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7718810 0.82 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1014665 0.82 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0998472-A1 SUBSTITUTED 2-(BENZOARYL)PYRIDINES BASF AKTIENGESELLSCHAFT (DE) 2000-05-10 EP claimed
WO-1999006394-A1 SUBSTITUTED 2-(BENZOARYL)PYRIDINES BASF AKTIENGESELLSCHAFT (DE) 1999-02-11 WO claimed
EP-0207241-B1 FABRIC INK RIBBON Pelikan Aktiengesellschaft (DE) 1991-04-10 EP claimed
US-4773778-A Fabric printer ribbon comprising a liquid vehicle containing a decolorizable Lewis acid/Lewis base complex PELIKAN AKTIENGESELLSCHAFT (DE) 1988-09-27 US claimed
CN-85106344-A Use contains the imaging system of the photosensitive microcapsules of 4-(4 '-aminophenyl)-pyridine compounds 1987-02-18 CN claimed
EP-0031257-B1 PYRIDYLANILINES ISHIHARA SANGYO KAISHA LTD. (JP) 1984-08-15 EP claimed
US-4331670-A PESTICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 1982-05-25 US claimed
EP-0031257-A2 Pyridylanilines ISHIHARA SANGYO KAISHA LTD. (JP) 1981-07-01 EP claimed
JP-5156193-A None JP disclosed
JP-11209205-A None JP disclosed
US-20260090269-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2026-03-26 US disclosed
US-20260090199-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2026-03-26 US disclosed
US-20250368891-A1 COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2025-12-04 US disclosed
US-20250359480-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2025-11-20 US disclosed
US-4028092-A Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthiophenylurea herbicides THE DOW CHEMICAL COMPANY (US) 1977-06-07 US disclosed
US-4026937-A Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio-phenylureas THE DOW CHEMICAL COMPANY (US) 1977-05-31 US disclosed
US-4003906-A Substituted pyridinyl methylthio or (methylsulfonyl)benzeneamines THE DOW CHEMICAL COMPANY (US) 1977-01-18 US disclosed
US-3991068-A Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthiophenylureas THE DOW CHEMICAL COMPANY (US) 1976-11-09 US disclosed
US-3987050-A SUBSTITUTED PYRIDINYLALKOXY-, PYRIDINYLALKYLSULFONYL AND PYRIDINYLALKYLTHIO-PHENYL-LOWER-ALKANAMIDES THE DOW CHEMICAL COMPANY (US) 1976-10-19 US disclosed
US-3931200-A Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenylureas THE DOW CHEMICAL COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090269-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME NR2E3, ARNT, AHR KDM4E 2236/4885LMNA 3348/4885CCR1 1287/4885
US-20260090199-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME AHR, NR2E3, ARNT KDM4E 3425/4885LMNA 3585/4885CCR1 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.