Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 16/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841044 | 0.85 | FKBP1A (0.62) | FKBP1A | |
| SCHEMBL28456852 | 0.82 | FKBP1A (0.56) | FKBP1APOLBMEN1KMT2A | |
| SCHEMBL28456850 | 0.82 | FKBP1A (0.56) | FKBP1APOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30719917 | 0.81 | FKBP1A (0.55) | FKBP1APOLBMEN1KMT2A | |
| Oxalic Acid SCHEMBL28447422 | 0.80 | POLB (0.58) | FKBP1APOLBMEN1KMT2A | |
| Oxalic Acid SCHEMBL28455046 | 0.80 | POLB (0.58) | FKBP1APOLBMEN1KMT2A | |
| SCHEMBL24710613 | 0.80 | FKBP1A (0.65) | FKBP1APOLBMEN1KMT2ASIGMAR1 | |
| SCHEMBL1852673 | 0.79 | FKBP1A (0.64) | FKBP1APOLBSIGMAR1 | |
| SCHEMBL7106180 | 0.78 | FKBP1A (0.62) | FKBP1APOLBSIGMAR1 | |
| SCHEMBL3786414 | 0.78 | FKBP1A (0.73) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003514-A1 | CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999004794-A1 | CYCLIC AMINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1999-02-04 | — | — | WO | disclosed |