Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 13/20 | 0.39 |
| ▸ | BRS3 | P32247 | 5/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194512 | 0.92 | PTGS1 (0.37) | CTSABRS3CAPN1 | |
| SCHEMBL8185614 | 0.89 | BRS3 (0.43) | BRS3 | |
| SCHEMBL8193530 | 0.85 | BRS3 (0.35) | CTSABRS3 | |
| SCHEMBL8194554 | 0.84 | CTSA (0.34) | CTSACAPN1 | |
| SCHEMBL7561395 | 0.83 | CTSA (0.38) | CTSACAPN1 | |
| SCHEMBL8185553 | 0.79 | MAPK8 (0.34) | CTSABRS3 | |
| SCHEMBL7564344 | 0.78 | CYP19A1 (0.40) | CTSA | |
| SCHEMBL8185309 | 0.76 | PTGDR2 (0.35) | BRS3CAPN1 | |
| SCHEMBL7568388 | 0.75 | NAMPT (0.36) | CTSA | |
| SCHEMBL8199598 | 0.74 | CTSA (0.39) | CTSABRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |